According to tradition, towards the end of her life the Blessed Virgin moved from Jerusalem to Ephesus (in modern-day Turkey). No longer able to retrace the steps of her Son’s passion where they actually occurred, she set up an identical Stations of the Cross on her property using stones and markings. This became the first devotional Stations of the Cross. This is described in detail by Blessed Anne Catherine Emmerich according to her visions.
Historically, this Marian title is closely connected with the Church triumphing over her enemies through the protection and intercession of the Blessed Mother. Mary under her title Help of Christians was the special devotion of St. John Bosco and the Salesian order he founded. This was based on his Prophetic Vision of the Two Columns in which he saw the Church being saved through its devotion to Mary, under her title Help of Christians, and the Holy Eucharist.